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Wednesday, July 25, 2012

KEY CLINICAL CHEMISTRY 3 2012-2013 PRELIM EXAMS




KEY CLINICAL CHEMISTRY 3  2012-2013 PRELIM EXAMS

I.                   Identification:  (1 pt. each)

1.      _____PROTEIN___________________________________ The chemical nature of enzymes.
2.      PEPTIDE, STEROIDS, EICOSANOIDS, AMINE_____The chemical nature of hormones.
3.      _____CORTISOL BINDING GLOBULIN____________  The major binding protein of cortisol.
4.      _____T3, OR TRIIDOTHYRONINE________________ The more potent thyroid hormone.
5.      ______RT3U OR THBR____________________________  The test that measures the available binding sites of TBG.
6.      ______EMIT ______________________________________  The test that does not need the separation of the free T4 from the bound T4.
7.      ______SOLID PHASE ANTIBODY___________________  This test makes use of two antibody phases.
8.      ______ULTRASOUND______________________________ This test makes use of high frequency sound waves to determine the organ dysfunction.
9.      ______ANS_______________________________________ This is the reagent that separates T4 from the bound.
10.  ______SEE NOTES__________________________________ Give one precaution for Thyroid hormone determination.

TEST II. MULTIPLE CHOICE ANSWERS

1. D
11. D
21. D
31. C
41. K
51. Q, R
2. D
12. D
22. BONUS
32. D
42. T
52. D
3. C
13. C
23. D
33. C
43. F
53. D
4. D
14. B
24. B
34. D
44. C
54. D
5. C
15. A
25. C
35. D
45. G
55. D
6. A
16. B
26. A
36. B
46. D

7. C
17. B
27. B
37. D
47. F, P

8. D
18. B
28. C
38. BONUS
48. L

9. D
19. C
29. D
39. B
49. I

10. B
20. B
30.B
40. A
50. E, M


TEST III. MATCHING TYPE

1.      A, B                                    6.   A
2.      B                                         7.   A
3.      A, B                                    8.   B
4.      A                                         9.   B
5.      A                                        10.   A

TEST IV CASE ANALYSIS:

1.      WHAT FURTHER TESTS WOULD YOU RECOMMEND? DEFEND YOUR ANSWER.

FT3
FT4
TSH
THBR
CORTISOL

THE SYMPTOMS OF THE PATIENT MIMIC THAT OF A PERSON WITH THYROID AND ADRENAL DYSFUNCTION. SINCE THE LABORATORY RESULTS ARE ALL NORMAL, EXCEPT FOR HEMOGLOBIN, WHICH IS SLIGHTLY BELOW NORMAL VALUES FOR MALE, THE NEXT OPTION IS TO CONSIDER METABOLIC DISORDERS.

THE SLIGHTLY LOW HEMOGLOBIN VALUES OF THE PATIENT IS NOT CRITICAL BECAUSE THE BLOOD MORPHOLOGY SHOWED NORMAL CELLS, HENCE, ITS SLIGHTLY LOW VALUE  COULD BE BECAUSE OF LESS SERIOUS CAUSES LIKE MALNUTRITION, AND SIMILAR CASES.


2.      WHAT WOULD BE THE MOST LIKELY DIAGNOSIS? DEFEND YOUR ANSWER.

THE MOST LIKELY DIAGNOSIS WOULD BE HYPERTHYROIDISM AND HYPERADRENALISM, MOST LIKELY, GRAVE’S DISEASE.

THE OVERALL DATA OF THE PATIENT SHOULD BE COLLATED FIRST (HISTORY, PHYSICAL SYMPTOMS, LABORATORY RESULTS, AND OTHER DIAGNOSTICS TESTS) BEFORE COMING TO A CONCLUSION.


FOR THE RIA METHOD REFER TO NOTES.

FOR THE TRANSCRIPTION- PLS RESEARCH